Precision gas analytics · Made in Germany

One technology
platform.
A world of
applications.

We make the invisible measurable. ION-GAS develops instruments and software for the rapid, highly sensitive detection of trace substances in breath and other gases.

Founded in 2014. A spin-off from TU Dortmund University and the Leibniz Institute for Analytical Sciences – ISAS.

FROM THE LAB TO THE FIELDIONdrug mobile cannabis breath analysis system
IONdrugMobile cannabis breath screening
~90 secResult after sampling
2014

Year founded

€2.15 million

Research funding

1,000+

Breath measurements

4

Application areas

Our applications

Small traces.
Meaningful insights.

From breath screening to gas quality and bioprocess research, our platform brings analytical science into practical applications.

Breath analysis

IONdrug

A mobile cannabis breath screening system designed for use on site, with non-invasive sampling and rapid analysis.

Explore IONdrug

GC-IMS combines rapid separation with sensitive detection. Potential applications include workplace screening, fleet operations and authorities. Screening results do not themselves establish impairment.

Gas quality

H₂IMS

A system developed for continuous hydrogen quality monitoring, supporting the identification of trace contaminants.

Explore H₂IMS

Hydrogen quality is an important parameter across its supply and use. H₂IMS applies ION-GAS analytical expertise to monitoring gas quality.

Research & development

Beyond detection

Collaborative research into bioprocess monitoring and control, and non-invasive infection diagnostics.

Explore our research

MiKI explores GC-IMS monitoring and control of fermentation processes. ViBa-IMS investigates characteristic markers associated with viral and bacterial infections. These are research applications.

Inside the technology

From a gas sample
to an analytical fingerprint.

GC-IMS brings together two complementary separation techniques. Gas chromatography separates compounds over time; ion mobility spectrometry distinguishes their ions by movement through a drift gas in an electric field. Together, they reveal patterns that our instruments and software can analyse.

01 / SAMPLE

Capture the sample

Breath, gas or volatile compounds released from a material. Sampling and optional preconcentration are adapted to the analytical question.

02 / GC

Separate over time

Compounds pass through a chromatographic column at different rates, producing characteristic retention times.

03 / IMS

Measure ion mobility

After ionisation, ions move through a drift region. Their characteristic drift times provide a second analytical dimension.

04 / SOFTWARE

Interpret the pattern

Retention time, drift time and signal intensity form a fingerprint. Reference data and calibrated methods support identification and quantification.

Research IMS assembly showing the drift tube, electrical connections and gas tubing
Inside an IMS research assembly — the hardware behind the analytical principle.

A modular analytical platform

One principle.
Application-specific methods.

Our analytical toolbox combines sampling, optional microextraction or thermal desorption, chromatographic separation and IMS detection. The configuration is selected for the sample and the substances being investigated.

This flexibility supports applications ranging from cannabis breath screening and hydrogen quality monitoring to research into microbial signatures and bioprocesses.

Sampling & preparationGC / micro-GC / MCCIMS detectionMethod development
Explore the analytical detail

A GC-IMS measurement combines chromatographic retention time with ion drift time. Signal intensity adds information that can be related to concentration through appropriate calibration. Measurement time, sensitivity and interpretation depend on the instrument configuration, sample and validated analytical method.

Medical research applications require application-specific studies and validation before clinical use. Research into bacterial identification and infection markers does not imply that these applications are available as approved diagnostic products.

Research & application areas

A platform with
room to go further.

Our research portfolio explores how gas and breath analysis can support healthcare, environmental monitoring and the detection of hazardous compounds.

01

Bacterial identification

Research into bacterial identification, infections including pneumonia, and antimicrobial resistance.

02

Breath-based diagnostics

Exploring breath analysis in nephrology, diabetes and the investigation of infection-related markers.

03

Medication monitoring

Research into analytical applications involving propofol, isoflurane, sevoflurane and ketamine.

04

Substance-use screening

Mobile cannabis breath screening with IONdrug, alongside research applications involving alcohol.

Funded project portfolio

From clinical questions
to environmental insights.

Research topics across our funded projects include:

  • Identification of bacteria in blood culture bottles
  • Diagnosis of hospital-acquired infections through breath analysis
  • Identification and reduction of multidrug-resistant pathogens
  • Breath-based diagnostics in nephrology
  • Identification of antimicrobial resistance
  • Detection of hazardous compounds
  • Biodiversity monitoring

Medical applications described here are research and development areas. They do not imply that approved clinical diagnostic or medication-monitoring products are currently available.

Current & past research collaborations

Progress through
collaboration.

Our research brings together clinical institutions, universities, research organisations and industry partners across different projects.

Clinical collaborations

Universitätsmedizin Göttingen
Universitätsklinikum Carl Gustav Carus Dresden
Charité – Universitätsmedizin Berlin
Marien Hospital Herne
Helios Universitätsklinikum Wuppertal

Universities & research institutions

Fraunhofer IME
Justus Liebig University Giessen
Hamm-Lippstadt University of Applied Sciences
German Primate Center
Witten/Herdecke University
TU Dortmund University
Leibniz Institute for Analytical Sciences – ISAS
University of Bonn

Industry collaborations

AIRSENSE Analytics GmbH
Logic Way GmbH
Quh-Lab Lebensmittelsicherheit
Differential Bio GmbH
Fungtional.bio GmbH

Bioprocess monitoring & control

MiKI

GC-IMS analysis of fermentation exhaust gases to support metabolic monitoring and AI-based control of biotechnological food production.

Project period
November 2025 – October 2028
Consortium partners
Fraunhofer IME (coordinator), ION-GAS GmbH, Differential Bio GmbH, Justus Liebig University Giessen and Quh-Lab Lebensmittelsicherheit.
Explore the MiKI project

Infection diagnostics research

ViBa-IMS

Research into rapid, non-invasive breath analysis to distinguish viral and bacterial respiratory infections. ION-GAS investigates characteristic markers from laboratory virus cultures.

Consortium partners
Hamm-Lippstadt University of Applied Sciences, ION-GAS GmbH, AIRSENSE Analytics GmbH, Logic Way GmbH, Universitätsmedizin Göttingen, German Primate Center and Witten/Herdecke University.
Explore the ViBa-IMS project

About us

ION-GAS GmbH – A technology platform for breath analysis

Founded in 2014 as a spin-off from TU Dortmund University and the Leibniz Institute for Analytical Sciences (ISAS), ION-GAS GmbH develops instruments and software that rapidly detect trace substances in breath and other gases. Its technology combines gas chromatography with ion mobility spectrometry (GC-IMS).

Its lead commercial product, IONdrug, is a mobile cannabis breath test designed for use on site. According to the company, it delivers a result approximately 90 seconds after sampling. More than 1,000 breath measurements have been conducted, with devices used at music festivals and by police in Hamburg and North Rhine-Westphalia.

ION-GAS has sold already seven devices with a combined value of approximately EUR 500,000: two to universities in the United States, one to Saarland University, two to clinics in Spain and two for the AMMOD project at the University of Bonn. The real roll-out is expected to take place in 2027.

The company currently has six employees and plans to expand its core team to ten following the proposed capital raise, using external specialists for additional capacity.

The platform extends beyond cannabis testing. H₂IMS addresses continuous hydrogen quality monitoring, while research projects including MiKI and ViBa-IMS explore bioprocess control and non-invasive infection diagnostics. ION-GAS was named “Best Medical Diagnostics Analytical Devices Manufacturer – Europe” at the 2022 GHP Technology Awards.

ION-GAS has received EUR 2.15 million in research funding to date and expects a further EUR 680,000 from ongoing projects by 2028. Its business plan targets EUR 22.5 million in annual revenue by 2030 from cannabis testing devices alone; potential revenue from other pipeline products is excluded.

Management

Scientific expertise.
Experienced leadership.

Dr. Chandrasekhara Hariharan

Managing Director

Dr. Chandrasekhara Hariharan

Dr. Chandrasekhara Hariharan leads ION-GAS as its Managing Director. His published research covers GC-IMS applications in food characterisation, ecosystem monitoring and cannabis breath detection, connecting analytical science with practical applications.

Selected research publication
Dr. Wolfgang Vautz

Management Team

Dr. Wolfgang Vautz

Dr. Wolfgang Vautz is a member of the ION-GAS management team. His published research spans ion mobility spectrometry, cannabis breath detection and the analysis of volatile compounds, bringing scientific expertise across the company’s analytical technology platform.

Selected research publication
Sascha Liedtke

Management Team

Sascha Liedtke

Sascha Liedtke is a member of the ION-GAS management team. His published research includes GC-IMS applications in food analysis and the measurement of volatile compounds in plants, reflecting his involvement in the platform’s analytical applications.

Selected research publication

Get in touch

Let's make the
invisible measurable.

Talk to us about our instruments, an analytical challenge or a research collaboration.